SUPRARENALS IN EXPERIMENTAL DIABETES

Ensete superbum ameliorates renal dysfunction in experimental diabetes mellitus

Objective(s):Hyperglycemia mediated oxidative stress plays a key role in the pathogenesis of diabetic complications like nephropathy. In the present study, we evaluated the effect of ethanolic extract of Ensete superbum seeds (ESSE) on renal dysfunction and oxidative stress in streptozotocin-induced diabetic rats. Materials and Methods:Glucose, HbA1c, total protein, albumin, renal function mar...

Renal hypertrophy in experimental diabetes.

The effect of short-term diabetes, 5 days after the administration of streptozotocin, on renal growth and the activity of alternative pathways of glucose metabolism was studied in immature (21-day-old) rats and in adult rats. The kidney weight increased by 28% in the adult diabetic rats, but by only 10% in the immature diabetic rats, relative to their age-matched control groups. The flux of glu...

Curcumin Derivatives in Experimental Diabetes

Curcumin, from the rhizomes of Curcuma longa, is characterized by its anti-diabetic properties, among other healing properties primarily because it is a relatively safe and inexpensive. The application of curcum derivatives for the treatment of experimental diabetes and its complications has paced long ways. Curcumin and its derivatives affect most of aspects of diabetes; including plasma insul...

Cardiovascular control in experimental diabetes.

Several studies have reported impairment in cardiovascular function and control in diabetes. The studies cited in this review were carried out from a few days up to 3 months after streptozotocin administration and were concerned with the control of the circulation. We observed that early changes (5 days) in blood pressure control by different peripheral receptors were maintained for several mon...

Indigenous Drugs in Experimental Diabetes